Featured Application Notes
AN-SC-06 – Application of Alvetex Scaffold for 3D Culture of Osteocytes to Investigate Regulation of Bone in Normal and Simulated Microgravity Environments
In this application note we describe work carried out by Jordan Spatz, a PhD student at Harvard-MIT Division of Health Sciences & Technology (HST) working with Professor Paola Divieti-Pajevic. Some of this data has been previously presented as a scientific poster at the 2012 Annual Society for Bone and Mineral Research meeting. We would like to thank Jordan and Paola for allowing us to show these data and images of their work on the 3D culture of Osteocytes.
AN-SC-01 – Formation of Mesenchymal Tissues in Alvetex Scaffold Derived From Stem Cells and Established Cell Lines
Based on an increasing body of evidence, it is generally accepted that culturing cells in three dimensional (3D) models can lead to superior cell viability, differentiation and function compared to existing conventional culture systems where cells largely grow as monolayers on two dimensional (2D) substrates. These enhanced qualities are important for the retention of the in vivo-like cell phenotype, cell differentiation potential and subsequent functionality as required for downstream applications. Here we demonstrate the application of AlvetexScaffold technology for the growth and differentiation of mesenchymal cells and the formation of differentiated tissues.
Alvetex Scaffold is currently available in the following formats. The formats relevant to bone are highlighted.
|Alvetex Scaffold 12 well plate||AVP002-2||2 x 12 well plates, individually sterile blister packed|
|Alvetex Scaffold well insert holder and deep petri-dish||AVP015-2||2 units, individually sterile blister packed|
|Alvetex Scaffold 6 well insert||AVP004-12||12 inserts, individually sterile blister packed|
|Alvetex Scaffold 12 well insert||AVP005-12||12 inserts, individually sterile blister packed|
|Alvetex Scaffold 24 well plate||AVP006-2||2 x 24 well plates, individually sterile blister packed|
|Alvetex Scaffold 96 well plate||AVP009-2||2 x 96 well plates, individually sterile blister packed|
Alvetex Scaffold is sold through various scientific labware distributors around the world.