Recent scientific paper reports preclinical anti-cancer drug investigation on colorectal cancer cells grown in 3D culture using Alvetex Scaffold


In a paper recently published in the PLOS ONE (Public Library of Science) journal, researchers at the Heidelberg University Hospital, Germany, investigated the effects of anti-cancer drugs on inhibition of migration and invasion of colorectal cancer cells grown in 3D culture using Alvetex Scaffold. Their research has led them to recommend investigating pan-Bcl-2 inhibition as a promising approach for clinical trials.


More information:

Pan-Bcl-2 Inhibitor Obatoclax Delays Cell Cycle Progression and Blocks Migration of Colorectal Cancer Cells

Bruno Christian Koehler,  Anna-Lena Scherr,  Stephan Lorenz,  Christin Elssner,  Nicole Kautz,  Stefan Welte,  Dirk Jaeger,  Toni Urbanik,  Henning Schulze-Bergkamen

PLoS ONE 9(9): e106571.
DOI: 10.1371/journal.pone.0106571
Published September 05, 2014