Product Code: 04-0014
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A83-01 is a selective inhibitor of the transforming growth factor-beta (TGF-β) type I receptor ALK5, the Activin/Nodal receptor ALK4, and the nodal receptor ALK71. It inhibits the TGF-β-induced epithelial-to-mesenchymal transition (EMT) via the inhibition of Smad2 phosphorylation.
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