Product Code: 04-0041
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DAPT (a.k.a GSI-IX or LY-374973) is a cell-permeable dipeptide that inhibits γ-secretase and indirectly inhibits Notch, a γ-secretase substrate. DAPT has been shown to dose-dependently decrease amyloid-β levels via inhibition of γ-secretase in both plasma and cerebral spinal fluid.
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