Sedgefield, UK. 18th November 2010. Reinnervate, an innovative life sciences company driving the adoption of routine 3D cell culture, today announced the appointment of Classic Industries Europe for the commercial assembly and packaging of Alvetex® plates for 3D cell culture applications. Reinnervate is currently gearing up for the first launch of Alvetex at the Cell-Based Assay conference in London on 22-23 November 2010.
Under the terms of the agreement, Reinnervate will continue to manufacture Alvetex at its new purpose-built research and production facility at NETPark near Sedgefield, UK. The final product will be assembled by Classic Industries Europe at its GMP production facility in nearby Barnard Castle then blister packed and sterilised in preparation for distribution and sale. Classic Industries Europe has been operating in County Durham for over 20 years and forms part of the US-headquartered Classic Industries Inc., a leading supplier of plastic components to the medical, pharmaceutical and healthcare industries worldwide.
Alvetex is a unique and proprietary scaffold that enables routine 3D cell culture in the lab, i.e. more akin to the way cells grow in tissues in the human body than conventional 2D cell culture technologies where cells grow in flat sheets. The use of Alvetex-derived 3D cell cultures is expected to provide greater insight into how cells behave in the body in response to external factors (such as drug candidates) than is currently possible with existing technologies.
Alvetex is compatible with a variety of standard cell culture formats including multi-well plates and well inserts. Reinnervate will initially launch Alvetex in a 12-well plate format, and is developing a range of formats for multiple, potential applications in academia and in the pharmaceutical and related sectors, including high-throughput drug screening. These products are designed to be available as ready-to-use, off-the-shelf products that can sit alongside existing consumable cell culture plastic-ware in laboratories. Reinnervate has already begun discussions with major distributors of cell culture products in the UK and overseas to sell Alvetex. Ashley Cooper, CEO of reinnervate, commented: “The appointment of Classic Industries for the production of the Alvetex 12-well plate is a major step towards the full commercial launch of our Alvetex technology platform. Alvetex products are designed to enable the use of genuine 3D cell culture routinely in academic and industry laboratories around the world. To support the launch of Alvetex we will be looking to recruit up to 30 new employees to rapidly expand our production and sales operations over the next 12 months.”
John Pearson, General Manager of Classic Industries Europe, added:“We are very pleased to be working with reinnervate to produce its innovative Alvetex product range. We are now engaged in full commercial production of the Alvetex 12-well plate and hope that this will represent the start of a strong and ongoing relationship between the two companies.”
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Reinnervate is an innovative life sciences company dedicated to making routine 3D cell culture a reality for researchers in academia and in the pharmaceutical and related industries.
Reinnervate’s core technology is Alvetex®, a unique and proprietary scaffold that enables routine 3D cell culture in the laboratory. Alvetex provides a nanoscale environment that supports genuine homogeneous 3D cell growth. Cells grown using Alvetex form complex 3D tissue cultures, which more closely mimic normal in vivo cell growth and the formation of tissues in the body. The use of Alvetex-derived 3D cell cultures can provide researchers with greater insight into how cells behave in the body in response to external factors (such as drug candidates) than is currently possible with existing 2D or other emerging 3D cell culture technologies.
Reinnervate has generated significant data, which have been published extensively in peer-reviewed publications, exemplifying the use of Alvetex in a large number of cell types and applications. Alvetex is being developed for commercialisation in a range of formats and is due to be launched in 2010.
Reinnervate is also using its cell biology expertise to generate a library of synthetic small molecules that mediate stem cell differentiation in vitro. The first of these small molecules, ec23®, is commercially available and offers the potential for robust and reproducible differentiation of neural cell types.
Reinnervate was founded in 2002 based on the pioneering research of Professor Stefan Przyborski and his lab at Durham University, UK, and has been funded by Northstar Ventures, management and private investors.
About Classic Industries
Classic Industries Europe have been in business at Middleton-in-Teesdale, near Barnard Castle, County Durham for over 20 years, and are a leading supplier of plastic components to the Medical, Pharmaceutical and Healthcare Industries.
The County Durham facility includes:
- 20 all electric Fanuc Injection Moulding machines
- Printing, welding and assembly capability
- Class 7 clean rooms
- Committed, highly flexible and experienced workforce of 50 people
- Blue chip medical, Pharmaceutical and Healthcare customer base
Background on Classic Industries Inc.
- A 40 year history
- World class medical, pharmaceutical and healthcare OEM’s
- 500 + employees
- Headquarters in Latrobe, Pennsylvania
- Plants in Texas, Puerto Rico and China